FSU Maguire Medical Library Blog

Free Online Tool Helps Users Record and Share Research

A free clickstream recording Web service for researchers has launched, developed by two college graduates who had become frustrated by the inefficiency and redundancy of gathering research. iBreadCrumbs <http://www.ibreadcrumbs.com/> created by California State University, Fullerton <http://www.fullerton.edu/> graduates Reuben Fine and Rey Marques, is an online tool that allows teachers, researchers, and students to save and share their research with others.

Users download the free iBreadCrumbs toolbar, which runs only on FireFox <http://www.mozilla.com/en-US/firefox/>, search the Internet, and click on the Web pages visited to share with others. Users can also add notes and references to pages visited and save the Web history for others to see the sites and review the content they viewed. Those viewing the breadcrumbs can use any browser.

More information about iBreadCrumbs may be found at http://www.campustechnology.com/articles/63507

Google Health beta Launches

Jacqui Cheng writes: “Google Health opened up to the public May 19 after several months of private beta testing. The long-anticipated health records project now allows Google users to manage their doctor records, prescriptions, and test results, as well as find out information about drug interactions and search for new doctors. All you need is a Gmail account and a healthy dose of trust to get started with Google Health, although some are still skeptical about the terms of service.”  Read the compete article at http://tinyurl.com/46e6rf

Watch a cautious C|Net video (3:46) http://news.cnet.com/1606-2_3-50002344.html on the topic.

NIH Launches Undiagnosed Diseases Program

The National Institutes of Health (NIH) announced a new clinical research program that will aim to provide answers to patients with mysterious conditions that have long eluded diagnosis. Called the Undiagnosed Diseases Program, the trans-NIH initiative will focus on the most puzzling medical cases referred to the NIH Clinical Center in Bethesda, Md., by physicians across the nation.

For more information about the Undiagnosed Diseases Program, go to: http://rarediseases.info.nih.gov/Resources.aspx?PageID=31.  Physicians and patients with specific inquiries may call the NIH Clinical Center clinical information research line, at 1-866-444-8806.

SuccessTypes in Medical Education: A Program for Improving Academic Performance Now Available Online

John Pelley’s book, SuccessTypes in Medical Education:  A Program for Improving Academic Performance, is now in a free online version at http://www.ttuhsc.edu/SOM/success/successtypes%20in%20medical%20education.pdf.  It may be found by going to the library's "E-Books" page.  Remember, if you are off campus, be sure to click on the "Off-Campus Access (EZProxy)" link first.

In addition to providing a link to the book, Dr. Pelley’s web page http://www.ttuhsc.edu/SOM/success/, provides content related to teaching and other applications of personality type in health professions education.

E-Journal Titles Newly Available from MDConsult

The following e-journals are now available in MDConsult. These new titles may be found by going to the library's "E-Journals" page.  Remember, if you are off campus, be sure to click on the "Off-Campus Access (EZProxy)" link first.

• American Journal of Infection Control, February 2000-present
• American Journal of Opthalmology, 2004-present
• Anesthesia and Analgesia, 2000-present
• Clinical Journal of Pain, March 2000-present
• European Journal of Pain, 2000-present
• Heart Failure Clinics, April 2005-present
• Journal of Hospital Infection, 2000-present
• Journal of Infection, 2000-present
• Journal of Men’s Health, March 2008-present
• Journal of Pain, 2000-present
• Neuromodulation, 2002-present
• Nursing Clinics of North America, March 2002-present
• Paediatric Respiratory Reviews, March 2000-present
• Pain Medicine, March 2002-present
• Pain Practice, March 2002-present
• Pediatric Infectious Disease Journal, 2000-present
• Perioperative Nursing Clinics, March 2006-present
• PET Clinics, 2006-present
• Pulmonary Pharmacology and Therapeutics, February 2000-present
• Regional Anesthesia and Pain Medicine, 2000-present
• Respiratory Medicine, 2000-present
• Seminars in Anesthesia,  Perioperative Medicine and Pain, March 2000-present
• Sleep Medicine Clinics of North America, March 2006-present
• Sleep Medicine Reviews, February 2000-present
• Techniques in Regional Anesthesia and Pain Management, 2000-present
• Thorax, 2000-present
• Tuberculosis, 2001-present
• Ultrasound Clinics, 2006-present
• Urology, 2004-present

MedlinePlus Multilingual Enhancement

  On May 7, 2008, MedlinePlus will debut a multilingual feature, providing access to high quality health information in languages other than English and Spanish. This new service benefits people who prefer to read consumer health information in their native language. It also helps the information professionals and health care providers who serve them. Over the years, many of you have requested this enhancement. Your suggestions helped us to develop this important service.

The new collection contains over 2,500 links to information in more than 40 languages and covers nearly 250 Health Topics. Continuous growth is expected.  The link to the new collection is http://www.nlm.nih.gov/medlineplus/languages/languages.html

Users can navigate the new collection of health information in multiple languages either by language or by topic. A page listing all of the languages covered will be linked from the MedlinePlus homepage. Users can browse these languages or link to the page listing all of the topics covered. In addition, a languages box will display on the English Health Topic pages. The languages box lists the languages with links on that topic in MedlinePlus. The languages box also links users to the collection of health information in multiple languages. Users can also search the new collection of health information in multiple languages. A new collection called Multiple Languages appears on the MedlinePlus search results pages.  Look for an update to the MedlinePlus Search Tips in the near future.

Finally, an interactive world map teaches users about the number of people who speak nine of the languages in the MedlinePlus collection. The languages - Arabic, Chinese, French, Korean, Russian, Somali, Spanish, Tagalog and Vietnamese - are among those most frequently spoken at home in the United States other than English, according to the U.S. census.

Additional OvidSP Tutorials Now Available

The Training team has created 6 additional online OvidSP tutorials. Now there are 7 available on the ovid.com training page as well as on the OvidSP Resource Center.

The tutorials are quick (2-4 minutes in length), end-user friendly learning tools covering everything from the basics of getting started with OvidSP to tips on using each Search Mode to a brief introduction to the Search Tools (requires the flash player):

• Select a Database 
• Search Page Overview 
• Basic Search Overview 
• Advanced Search Overview 
• Search Fields Overview 
• Find Citation Overview 
• Search Tools Overview 

SCImago Journal & Country Rank: Journal Rankings Based on Scopus Data

The new SCImago Journal & Country Rank system utilizes data from Elsevier's Scopus database to produce a variety of scholarly journal rankings. For example, you can rank journals by their h index in a particular subject area, such as Family Practice.  The h-index is an index that quantifies both the scientific productivity and the scientific impact of a journal (it is also applicable to scientists, countries...). The index is based on the set of the journal's most quoted papers and the number of citations that they have received in others publications.

The Help page provides detailed information about the free service.

NCBI Entrez Global Search Portal

The National Center for Biotechnology Information and the National Library of Medicine maintain a portal to search and access two dozen databases and related products available via the Entrez system. This portal page enables you to find information on a topic, including a gene, disease, or other biomedical topic, by searching all 24 databases at once rather than each individually. To get to the Entrez Portal it is best to first access a FSU COM Sponsored PubMed link (found in the scroll box on the library's main page), then to click on "About Entrez" at the top of the left hand column of the screen.  This will allow you to access full-text articles via the PubMed LinkOut service.

	PubMed: Literature database for biomedical information from 1955-present.  Includes MEDLINE and affiliated databases as well as publisher-submitted citations, totaling more than 14 million articles.  Use a UNC-sponsored link to get to full-text articles.
	PubMed Central: Repository of more than 75 free full-text journals in HTML and PDF format.  Many are new, online-only journals (ex: BioMedCentral titles); others are historically print journals (ex: BMJ).  Print journals may not have complete back issues or most recent issue available.
	Books: "Online bookshelf" of 30 titles (as of November 2003) covering a range of subjects in biomedicine, including Genes and Disease, Human Molecular Genetics, and Molecular Biology of the Cell.  Most are included as e-books in the UNC Catalog.
	OMIM: Online Mendelian Inheritance in Man provides curated and interlinked reviews of genetic diseases and conditions.  OMIM links to PubMed records for each article cited, to other OMIM articles, and to sequence and genetic mapping data. Some links go to external (non-NCBI) databases, including JAX.
	Nucleotide: This section allows simultaneous searching of the major nucleotide (DNA & RNA) databases available from the NCBI, including GenBank (updated nightly with records from EMBL and DDBJ), RefSeq (the curated sequence database), and PDB. Records in RefSeq include brief notes for gene function, polymorphisms/SNPs, conserved regions, functional regions, chromosomal locus, and literature references.
	Protein: Search many major protein/amino acid sequence databases as once, including Protein Data Bank (PDB), SwissProt, Protein Information Resource (PIR), and annotated sequence records from GenBank and RefSeq.
	Genome: NCBI has [approximately] whole genome data for a growing number of species, viruses, and plasmids located here.  Tools available in this section include the MapViewer (contiged sequence maps with annotations and links to other databases internal and external to NCBI), TaxPlot, COGs, and whole genome BLAST. NOTE: This section is still under development!
	Structure: The main component of this database is the Molecular Modelling Database, which contains 20,000 3D macromolecular structures for proteins and polynucleotides.  Some are available for VAST (Vector Alignment Search Tool) and PDBeast (taxonomy by structure) research.
	Taxonomy: Any biological species represented by at least one sequence in GenBank is classified here based on cladistic analysis of genetic divergence from other species either in the complete tree or selected by the researcher.  The species-specific page has nice links to external taxonomy databases as well as a complete (estimated) lineage for the species.
	SNP: AKA dbSNP, this database collects information about single nucleotide polymorphisms for genes in RefSeq and GenBank. Data includes frequency, location, and effect. SNPs can be searched by gene, function, chromosome, weight, and detection method.
	Gene: This database is still under development.  It allows you to search for genes by sequence and/or in the Map Viewer. Results are presented in a clear graphical and mapped fashion, with data pulled from a number of other databases.  Similar to, and may eventually replace, LocusLink.
	UniGene: This database clusters related genes to represent the uniqueness or stability of a gene across multiple species.  Computations are done (in advance) using BLAST comparisons.  Records include related information such as expression in tissues, chromosomal locus, and links to SAGE Genie.
	CDD: The Conserved Domain Database draws data from a variety of derivative protein databases, including Pfam, Smart, and COG.  Computations are done (in advance) using BLAST to determine conserved regions of protein sequence, which can then be compared visually using the CN3D viewer.  This databases also uses CDART (the Conserved Domain Architecture Retrieval Tool) to compare possible conserved domains to determine function.
	3D Domains: This database is part of the Molecular Modelling Database that is searchable in the Structure section.  It provides information about compact structural domains of proteins that can be compared using VAST.
	UniSTS: Known primers (based on Sequence Tagged Sites, or STS's) are cataloged and annotated in this database. Included in each record are the 5' and 3' primer sequences, estimated product size and base pair location, mapping information, and links to other NCBI sites about the gene sequence in question.
	PopSet: This database uses DNA sequences to analyze the evolutionary relatedness of a population.  This is helpful both for taxonomic research and epidemiology (ex: the "evolution" of SARS).  Some sets are aligned using BLAST but many are not.
	GEO: The Gene Expression Omnibus provides molecular abundance profiles based on expression microarrays using tissue samples.
	GEO DataSets: This is the curated version of GEO, where sets of related records from that database have been combined into meta-expression analyses.  The datasets do not always follow expected groupings.
	Homologene: A system for automated detection of homologs among the annotated genes of several completely sequenced eukaryotic geneomes.
	Cancer Chromosomes: Three databases, the NCI/NCBI SKY/M-FISH & CGH Database, the NCI Mitelman Database of Chromosome Aberrations in Cancer, and the NCI Recurrent Aberrations in Cancer, are now integrated into NCBI's Entrez system as Cancer Chromosomes. Search for cytogenetic, clinical, and/or reference information.
	PubChem Substance: This database contains descriptions of chemical samples, from a variety of sources, and links to PubMed citations, protein 3D structures, and biological screening results that are available in PubChem BioAssay. If the contents of a chemical sample are known, the description includes links to PubChem Compound.
	PubChem Compound: This database contains validated chemical depiction information provided to describe substances in PubChem Substance. Structures stored within PubChem Compounds are pre-clustered and cross-referenced by identity and similarity groups. Additionally, calculated properties and descriptors are available for searching and filtering of chemical structures.
	PubChem BioAssay: Contains bioactivity screens of chemical substances described in PubChem Substance.  It provides searchable descriptions of each bioassay, including descriptions of the conditions and readouts specific to that screening procedure.

ACP Journal Club Merging with Annals of Internal Medicine Beginning May 20, 2008

ACP Journal Club will appear in Annals of Internal Medicine beginning with the May 20th issue.  It will appear as a "center well", meaning a dedicated body of material in the center of the journal.  The format will be very close, if not the same as it appears now in its separate publication.  It will have a table of contents at the beginning of the well.  On the table of contents for Annals it will simply be listed as ACP Journal Club and the beginning page number.  The pagination within the well will be JC-1, 2, etc.  It will also mean that you will receive ACP Journal Club content once a month rather than its previous cycle resulting in more frequent publication of material.